Michele R. Isaacson, age 59, of Crossville, passed away April 4, 2021 at her home. She was previously employed by Roane Medical Center as a registered nurse for many years. She was preceded in death by her husband: Laurin Isaacson; father: Walter Roberts; and brother: Kenny Roberts. She is survived by her mother: Renee Selinger; brother: Richard Roberts (Victoria); sisters: Denise Aktchourine (Dimitri) and Donna Gentry Muse (Nick); niece: Molly Gentry; nephews: Drake Gentry, Cody Tolley (Devon) and Jacob Roberts; great-niece: Mavree Tolley; and a host of other friends and loved ones. Michele’s wishes to be cremated are being honored. A private service will be held at a later date. In lieu of flowers, the family requests that donations be made in her memory to the ALS Foundation at www.als.org/donate or by mail at The ALS Association, P.O. Box 37022 Boone, IA 50037-0022. Obituary and arrangements by Davis Funeral Home in Harriman.